mouse STK36 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Stk36.
shADV-273348
Ad-m-STK36-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Stk36 (serine/threonine kinase 36). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700112N14Rik; B930045J24; FU; Fused; mKIAA1278
Description (Vector)
Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia.
Gene ID
269209
Gene Name (Vector)
serine/threonine kinase 36
Gene Symbol
Stk36
ORF Size (aa)
3162
ORF Size (bp)
3162 bp
RefSeq ID
NM_175031
RefSeq Synonyms
NM_175031, BC058698, BC043103,
Species
mouse
UniGene ID
Mm.310974
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.