mouse SREBF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Srebf1.
shADV-273127
Ad-m-SREBF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Srebf1 (sterol regulatory element binding transcription factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADD1; bHLHd1; SREBP-1a; SREBP1; SREBP1c
Description (Vector)
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Gene ID
20787
Gene Name (Vector)
sterol regulatory element binding transcription factor 1
Gene Symbol
Srebf1
ORF Size (aa)
3405
ORF Size (bp)
3405 bp
RefSeq ID
NM_011480
RefSeq Synonyms
NM_011480, NM_001313979, BC056922,
Species
mouse
UniGene ID
Mm.278701
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.