mouse SLIT1 shRNA silencing Adenovirus

Name
Ad-m-SLIT1-shRNA

Cat No
shADV-272571

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Slit1.

shADV-272571

Ad-m-SLIT1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Slit1 (slit homolog 1 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

mKIAA0813; Slil1

Description (Vector)

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

Gene ID

20562

Gene Name (Vector)

slit homolog 1 (Drosophila)

Gene Symbol

Slit1

ORF Size (aa)

4593

ORF Size (bp)

4593 bp

RefSeq ID

NM_015748

RefSeq Synonyms

NM_015748, BC062091, BC057131,

Species

mouse

UniGene ID

Mm.40322

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.