human NEIL2 Over-expression AAV

Name 
AAV-h-NEIL2
Cat No 
AAV-216564
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NEIL2.

AAV-216564
AAV-h-NEIL2

Ready-to-use AAV expressing Human NEIL2 (nei like DNA glycosylase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NEH2; NEI2
Description (Vector)
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 (PubMed 12509226))(supplied by OMIM, Mar 2008)
Gene ID
252969
Gene Name (Vector)
nei like DNA glycosylase 2
Gene Symbol
NEIL2
HGNC ID
HGNC:18956
ORF Size (aa)
999
ORF Size (bp)
999 bp
RefSeq ID
NM_145043
RefSeq Synonyms
NM_145043, NM_001135748, NM_001135747, NM_001135746, BC013964, BC013952,
Species
human
UniGene ID
Hs.293818

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.