mouse SEMA7A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Sema7a.
shADV-271603
Ad-m-SEMA7A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sema7a (sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2900057C09Rik; CDw108; H-Sema-L; M-Sema-L; Semal
Description (Vector)
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Gene ID
20361
Gene Name (Vector)
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
Gene Symbol
Sema7a
ORF Size (aa)
1995
ORF Size (bp)
1995 bp
RefSeq ID
NM_011352
RefSeq Synonyms
NM_011352, BC057875,
Species
mouse
UniGene ID
Mm.335187
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.