mouse SCN5A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Scn5a.
shADV-271451
Ad-m-SCN5A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Scn5a (sodium channel, voltage-gated, type V, alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mH1; Nav1.5; Nav1.5c; SkM1; SkM2
Description (Vector)
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.
Gene ID
20271
Gene Name (Vector)
sodium channel, voltage-gated, type V, alpha
Gene Symbol
Scn5a
ORF Size (aa)
6063
ORF Size (bp)
6063 bp
RefSeq ID
NM_021544
RefSeq Synonyms
NM_021544, NM_001253860, BC172643,
Species
mouse
UniGene ID
Mm.103584
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.