mouse RPA2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Rpa2.
shADV-270821
Ad-m-RPA2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Rpa2 (replication protein A2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA409079; AI325195; AU020965; Rf-A2; RPA34
Description (Vector)
Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage|Function: Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Gene ID
19891
Gene Name (Vector)
replication protein A2
Gene Symbol
Rpa2
ORF Size (aa)
813
RefSeq ID
NM_011284
RefSeq Synonyms
NM_011284, BC004578,
Species
mouse
UniGene ID
Mm.2870
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.