human NDP Over-expression AAV

Name 
AAV-h-NDP
Cat No 
AAV-216455
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NDP.

AAV-216455
AAV-h-NDP

Ready-to-use AAV expressing Human NDP (NDP, norrin cystine knot growth factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EVR2; FEVR; ND
Description (Vector)
NDP encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy.
Gene ID
4693
Gene Name (Vector)
NDP, norrin cystine knot growth factor
Gene Symbol
NDP
HGNC ID
HGNC:7678
ORF Size (aa)
402
RefSeq ID
NM_000266
RefSeq Synonyms
NM_000266, BC029901,
Species
human
UniGene ID
Hs.522615

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.