mouse RAP2A shRNA silencing Adenovirus

Name 
Ad-m-RAP2A-shRNA
Cat No 
shADV-270133
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Rap2a.

shADV-270133
Ad-m-RAP2A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Rap2a (RAS related protein 2a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
5830461H18Rik
Description (Vector)
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Gene ID
76108
Gene Name (Vector)
RAS related protein 2a
Gene Symbol
Rap2a
ORF Size (aa)
552
RefSeq ID
NM_029519
RefSeq Synonyms
NM_029519, BC053003, BC049084, BC043066,
Species
mouse
UniGene ID
Mm.261448

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.