human NCALD Over-expression AAV
This is an AAV expressing Human NCALD.
AAV-216377
AAV-h-NCALD
Ready-to-use AAV expressing Human NCALD (neurocalcin delta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
NCALD encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.
Gene ID
83988
Gene Name (Vector)
neurocalcin delta
Gene Symbol
NCALD
HGNC ID
HGNC:7655
ORF Size (aa)
582
RefSeq ID
NM_032041
RefSeq Synonyms
NM_032041, NM_001040630, NM_001040629, NM_001040628, NM_001040627, NM_001040626, NM_001040625, NM_001040624, BC063428, BC036098, BC001131,
Species
human
UniGene ID
Hs.680132
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.