mouse PTF1A shRNA silencing Adenovirus

Name 
Ad-m-PTF1A-shRNA
Cat No 
shADV-269730
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ptf1a.

shADV-269730
Ad-m-PTF1A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ptf1a (pancreas specific transcription factor, 1a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bHLHa29; PTF1-p48; PTF1p48
Description (Vector)
Transcriptional activator. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells (By similarity). Plays an important role in cerebellar development.
Gene ID
19213
Gene Name (Vector)
pancreas specific transcription factor, 1a
Gene Symbol
Ptf1a
ORF Size (aa)
975
RefSeq ID
NM_018809
RefSeq Synonyms
NM_018809, BC138507, BC132505,
Species
mouse
UniGene ID
Mm.69647

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.