mouse PRKRA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Prkra.
shADV-269394
Ad-m-PRKRA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Prkra (protein kinase, interferon inducible double stranded RNA dependent activator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AV120107; lear; Pact; PRK; RAX
Description (Vector)
Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.
Gene ID
23992
Gene Name (Vector)
protein kinase, interferon inducible double stranded RNA dependent activator
Gene Symbol
Prkra
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_011871
RefSeq Synonyms
NM_011871, BC011311,
Species
mouse
UniGene ID
Mm.277250
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.