human NAGS Over-expression AAV

Name 
AAV-h-NAGS
Cat No 
AAV-216293
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NAGS.

AAV-216293
AAV-h-NAGS

Ready-to-use AAV expressing Human NAGS (N-acetylglutamate synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AGAS; ARGA
Description (Vector)
The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Gene ID
162417
Gene Name (Vector)
N-acetylglutamate synthase
Gene Symbol
NAGS
HGNC ID
HGNC:17996
ORF Size (aa)
1107
RefSeq ID
NM_153006
RefSeq Synonyms
NM_153006, BC111713,
Species
human
UniGene ID
Hs.8876

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.