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mouse PLSCR1 shRNA silencing Adenovirus

Name 
Ad-m-PLSCR1-shRNA
Cat No 
shADV-268903
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Plscr1.

shADV-268903
Ad-m-PLSCR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Plscr1 (phospholipid scramblase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MmTRA1a; MmTRA1b; Nor1; Tra1; Tra1a; Tra1b; Tras1; Tras2
Description (Vector)
PLSCR1 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system|Function: May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.
Gene ID
22038
Gene Name (Vector)
phospholipid scramblase 1
Gene Symbol
Plscr1
ORF Size (aa)
984
ORF Size (bp)
984 bp
RefSeq ID
NM_011636
RefSeq Synonyms
NM_011636, BC002017,
Species
mouse
UniGene ID
Mm.441702

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.