mouse PIKFYVE shRNA silencing Adenovirus

Name
Ad-m-PIKFYVE-shRNA

Cat No
shADV-268659

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Pikfyve.

shADV-268659

Ad-m-PIKFYVE-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pikfyve (phosphoinositide kinase, FYVE finger containing). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

5230400C17Rik; p235; Pip5k; Pip5k3; Pipk5k3; PipkIII

Description (Vector)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.

Gene ID

18711

Gene Name (Vector)

phosphoinositide kinase, FYVE finger containing

Gene Symbol

Pikfyve

ORF Size (aa)

6156

ORF Size (bp)

6156 bp

RefSeq ID

NM_011086

RefSeq Synonyms

NM_011086, NM_001310624, BC148367,

Species

mouse

UniGene ID

Mm.38370

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.