mouse PIAS4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Pias4.
shADV-268600
Ad-m-PIAS4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pias4 (protein inhibitor of activated STAT 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Pias-gamma; Piasg; PIASY
Description (Vector)
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
Gene ID
59004
Gene Name (Vector)
protein inhibitor of activated STAT 4
Gene Symbol
Pias4
ORF Size (aa)
1524
ORF Size (bp)
1524 bp
RefSeq ID
NM_021501
RefSeq Synonyms
NM_021501, BC025159,
Species
mouse
UniGene ID
Mm.34428
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.