mouse PFTK1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cdk14.
shADV-268456
Ad-m-PFTK1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cdk14 (cyclin-dependent kinase 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mKIAA0834; Pftk1
Description (Vector)
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Gene ID
18647
Gene Name (Vector)
cyclin-dependent kinase 14
Gene Symbol
Cdk14
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_011074
RefSeq Synonyms
NM_011074, NM_001310448, BC068134,
Species
mouse
UniGene ID
Mm.404502
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.