mouse PFN2 shRNA silencing Adenovirus

Name 
Ad-m-PFN2-shRNA
Cat No 
shADV-268451
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Pfn2.

shADV-268451
Ad-m-PFN2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pfn2 (profilin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Pfn
Description (Vector)
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Gene ID
18645
Gene Name (Vector)
profilin 2
Gene Symbol
Pfn2
ORF Size (aa)
423
ORF Size (bp)
423 bp
RefSeq ID
NM_019410
RefSeq Synonyms
NM_019410, BC024363,
Species
mouse
UniGene ID
Mm.271744

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.