mouse PAX4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Pax4.
shADV-268110
Ad-m-PAX4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pax4 (paired box 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Pax-4
Description (Vector)
Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Gene ID
18506
Gene Name (Vector)
paired box 4
Gene Symbol
Pax4
ORF Size (aa)
1008
ORF Size (bp)
1008 bp
RefSeq ID
NM_011038
RefSeq Synonyms
NM_011038, NM_001159926, NM_001159925, BC145169, BC145168, BC131908, BC131906,
Species
mouse
UniGene ID
Mm.8026
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.