human MYD88 Over-expression AAV

Name 
AAV-h-MYD88
Cat No 
AAV-216145
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MYD88.

AAV-216145
AAV-h-MYD88

Ready-to-use AAV expressing Human MYD88 (myeloid differentiation primary response 88). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MYD88D
Description (Vector)
MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Gene ID
4615
Gene Name (Vector)
myeloid differentiation primary response 88
Gene Symbol
MYD88
HGNC ID
HGNC:7562
ORF Size (aa)
891
ORF Size (bp)
891 bp
RefSeq ID
NM_002468
RefSeq Synonyms
NM_002468, NM_001172569, NM_001172568, NM_001172567, NM_001172566, BC013589,
Species
human
UniGene ID
Hs.82116

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.