mouse PA2G4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Pa2g4.
shADV-267968
Ad-m-PA2G4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pa2g4 (proliferation-associated 2G4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
38kDa; AA672939; Ebp1; Plfap
Description (Vector)
PA2G4 may play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity).
Gene ID
18813
Gene Name (Vector)
proliferation-associated 2G4
Gene Symbol
Pa2g4
ORF Size (aa)
1185
ORF Size (bp)
1185 bp
RefSeq ID
NM_011119
RefSeq Synonyms
NM_011119, BC046532,
Species
mouse
UniGene ID
Mm.4742
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.