mouse ORAI1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Orai1.
shADV-267681
Ad-m-ORAI1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Orai1 (ORAI calcium release-activated calcium modulator 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D730049H07Rik; orai-1; Tmem142a
Description (Vector)
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.
Gene ID
109305
Gene Name (Vector)
ORAI calcium release-activated calcium modulator 1
Gene Symbol
Orai1
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_175423
RefSeq Synonyms
NM_175423, BC023149,
Species
mouse
UniGene ID
Mm.218582
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.