human MYB Over-expression AAV

Name 
AAV-h-MYB
Cat No 
AAV-216117
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MYB.

AAV-216117
AAV-h-MYB

Ready-to-use AAV expressing Human MYB (MYB proto-oncogene, transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Cmyb; c-myb; c-myb_CDS; efg; oncogene AMV; proto-oncogene c-Myb; transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
Description (eCommerce)
c-Myb is a member of the MYB family of transcription factors. C-Myb contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. C-myb plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis [taken from NCBI Entrez Gene (Gene ID: 3093)].
Description (Vector)
MYB encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
Gene ID
4602
Gene Name (eCommerce)
MYB proto-oncogene, transcription factor
Gene Name (Vector)
MYB proto-oncogene, transcription factor
Gene Symbol
MYB
HGNC ID
HGNC:7545
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1923
ORF Size (bp)
1923 bp
Protein Name (eCommerce)
Transcriptional activator Myb
RefSeq ID
NM_005375
RefSeq Synonyms
NM_005375, NM_001161660, NM_001161659, NM_001161658, NM_001161657, NM_001161656, NM_001130173, NM_001130172, BC064955,
Research Areas
Cancer,Cell Cycle,Chromatin Remodeling,Histone Modification,Host-Virus Interactions,Immunology,Interleukin Signaling,Neurobiology,Neurodevelopment,PI3K/Akt Signaling,Prolactin Signaling,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,cell_cycle,transcription_translation,genetics,infectious_disease,immunology,signal_transduction,neurobiology,developmental_biology,signal_transduction,genetics,transcription_translation
Species
human
Target Sentence
c-Myb is a member of the MYB family of transcription factors. C-Myb contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. C-myb plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis [taken from NCBI Entrez Gene (Gene ID: 3093)].
UniGene ID
Hs.654446
UniProt ID (eCommerce)
P10242

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.