human MXD1 Over-expression AAV

Name 
AAV-h-MXD1
Cat No 
AAV-216103
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MXD1.

AAV-216103
AAV-h-MXD1

Ready-to-use AAV expressing Human MXD1 (MAX dimerization protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BHLHC58; MAD; MAD1
Description (Vector)
MXD1 encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
4084
Gene Name (Vector)
MAX dimerization protein 1
Gene Symbol
MXD1
HGNC ID
HGNC:6761
ORF Size (aa)
636
RefSeq ID
NM_002357
RefSeq Synonyms
NM_002357, NM_001202514, NM_001202513, BC143832, BC143831, BC117260, BC113531, BC098396, BC069433, BC069377,
Species
human
UniGene ID
Hs.468908

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.