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mouse NUMB shRNA silencing Adenovirus

Name 
Ad-m-NUMB-shRNA
Cat No 
shADV-266207
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Numb.

shADV-266207
Ad-m-NUMB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Numb (numb homolog (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Nb
Description (Vector)
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Gene ID
18222
Gene Name (Vector)
numb homolog (Drosophila)
Gene Symbol
Numb
ORF Size (aa)
1782
ORF Size (bp)
1782 bp
RefSeq ID
NM_010949
RefSeq Synonyms
NM_010949, NM_001272056, NM_001272055, NM_001136075, BC033459,
Species
mouse
UniGene ID
Mm.4390

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.