mouse NR2C1 shRNA silencing Adenovirus

Name 
Ad-m-NR2C1-shRNA
Cat No 
shADV-266042
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Nr2c1.

shADV-266042
Ad-m-NR2C1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nr2c1 (nuclear receptor subfamily 2, group C, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4831444H07Rik; 80.3; Eenr; TR2; Tr2-11
Description (Vector)
Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Gene ID
22025
Gene Name (Vector)
nuclear receptor subfamily 2, group C, member 1
Gene Symbol
Nr2c1
ORF Size (aa)
1773
ORF Size (bp)
1773 bp
RefSeq ID
NM_011629
RefSeq Synonyms
NM_011629, BC094580, BC090662,
Species
mouse
UniGene ID
Mm.107483

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.