mouse NR1I2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nr1i2.
shADV-266039
Ad-m-NR1I2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nr1i2 (nuclear receptor subfamily 1, group I, member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mPXR; PXR; PXR.1; PXR.2; PXR1; SXR
Description (Vector)
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
Gene ID
18171
Gene Name (Vector)
nuclear receptor subfamily 1, group I, member 2
Gene Symbol
Nr1i2
ORF Size (aa)
1296
ORF Size (bp)
1296 bp
RefSeq ID
NM_010936
RefSeq Synonyms
NM_010936, NM_001098404, BC137780, BC120796,
Species
mouse
UniGene ID
Mm.8509
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.