mouse NOD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nod1.
shADV-265907
Ad-m-NOD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nod1 (nucleotide-binding oligomerization domain containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C230079P11; Card4; F830007N14Rik; Nlrc1
Description (Vector)
Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathways activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB.
Gene ID
107607
Gene Name (Vector)
nucleotide-binding oligomerization domain containing 1
Gene Symbol
Nod1
ORF Size (aa)
2862
ORF Size (bp)
2862 bp
RefSeq ID
NM_172729
RefSeq Synonyms
NM_172729, NM_001171007, BC042670,
Species
mouse
UniGene ID
Mm.28498
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.