mouse NEK6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nek6.
shADV-265654
Ad-m-NEK6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nek6 (NIMA (never in mitosis gene a)-related expressed kinase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1300007C09Rik
Description (Vector)
Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.
Gene ID
59126
Gene Name (Vector)
NIMA (never in mitosis gene a)-related expressed kinase 6
Gene Symbol
Nek6
ORF Size (aa)
942
RefSeq ID
NM_021606
RefSeq Synonyms
NM_021606, NM_001159631, BC019524,
Species
mouse
UniGene ID
Mm.143818
Recently Viewed Products
AAV-m-PHACTR2-shRNA
Cat No: shAAV-268506
Ad-m-BLOC1S2
Cat No: ADV-254002
AAV-h-RNPEPL1-shRNA
Cat No: shAAV-221459
AAV-h-LIPT1-shRNA
Cat No: shAAV-230071
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.