mouse NDST1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ndst1.
shADV-265553
Ad-m-NDST1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ndst1 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200015G06Rik; b2b2230Clo; Hsst; NDST-1
Description (Vector)
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
Gene ID
15531
Gene Name (Vector)
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Gene Symbol
Ndst1
ORF Size (aa)
2649
ORF Size (bp)
2649 bp
RefSeq ID
NM_008306
RefSeq Synonyms
NM_008306, BC079561, BC066098,
Species
mouse
UniGene ID
Mm.181862
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.