mouse NANOS3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nanos3.
shADV-265429
Ad-m-NANOS3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nanos3 (nanos homolog 3 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
nos3
Description (Vector)
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
Gene ID
244551
Gene Name (Vector)
nanos homolog 3 (Drosophila)
Gene Symbol
Nanos3
ORF Size (aa)
525
RefSeq ID
NM_194059
RefSeq Synonyms
NM_194059, BC119514, BC119513,
Species
mouse
UniGene ID
Mm.216740
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.