mouse MYO1G shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Myo1g.
shADV-265333
Ad-m-MYO1G-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Myo1g (myosin IG). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E430002D17Rik
Description (Vector)
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity)|Function: Precursor of the minor histocompatibility antigen HA-2. More generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides to MHC class I or class II molecules and their expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation from HLA-identical sibling donor. GVHD is a frequent complication after bone marrow transplantation (BMT), due to mismatch of minor histocompatibility antigen in HLA-matched sibling marrow transplants. HA-2 is restricted to MHC class I HLA-A*0201.
Gene ID
246177
Gene Name (Vector)
myosin IG
Gene Symbol
Myo1g
ORF Size (aa)
3075
ORF Size (bp)
3075 bp
RefSeq ID
NM_178440
RefSeq Synonyms
NM_178440, BC113954, BC113755,
Species
mouse
UniGene ID
Mm.239554
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.