mouse MRC2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mrc2.
shADV-264866
Ad-m-MRC2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mrc2 (mannose receptor, C type 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Endo180; mKIAA0709; uPARAP
Description (Vector)
MRC2 may play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix co-operating with the matrix metalloproteinases (MMPs).
Gene ID
17534
Gene Name (Vector)
mannose receptor, C type 2
Gene Symbol
Mrc2
ORF Size (aa)
4440
ORF Size (bp)
4440 bp
RefSeq ID
NM_008626
RefSeq Synonyms
NM_008626, BC116642,
Species
mouse
UniGene ID
Mm.235616
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.