mouse MMP14 shRNA silencing Adenovirus

Name 
Ad-m-MMP14-shRNA
Cat No 
shADV-264720
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mmp14.

shADV-264720
Ad-m-MMP14-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mmp14 (matrix metallopeptidase 14 (membrane-inserted)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI325305; MMP-X1; MT-MMP-1; MT1-MMP; sabe
Description (Vector)
Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7.
Gene ID
17387
Gene Name (Vector)
matrix metallopeptidase 14 (membrane-inserted)
Gene Symbol
Mmp14
ORF Size (aa)
1749
ORF Size (bp)
1749 bp
RefSeq ID
NM_008608
RefSeq Synonyms
NM_008608, BC076638,
Species
mouse
UniGene ID
Mm.280175

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.