mouse MFN2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mfn2.
shADV-264560
Ad-m-MFN2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mfn2 (mitofusin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D630023P19Rik; Fzo
Description (Vector)
Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation.
Gene ID
170731
Gene Name (Vector)
mitofusin 2
Gene Symbol
Mfn2
ORF Size (aa)
2274
ORF Size (bp)
2274 bp
RefSeq ID
NM_133201
RefSeq Synonyms
NM_133201, NM_001285923, NM_001285922, NM_001285921, NM_001285920, BC046503,
Species
mouse
UniGene ID
Mm.154312
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.