mouse MCM3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mcm3.
shADV-264373
Ad-m-MCM3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mcm3 (minichromosome maintenance complex component 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AL033361; C80350; Mcmd; P1; p1.m
Description (Vector)
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Gene ID
17215
Gene Name (Vector)
minichromosome maintenance complex component 3
Gene Symbol
Mcm3
ORF Size (aa)
2439
ORF Size (bp)
2439 bp
RefSeq ID
NM_008563
RefSeq Synonyms
NM_008563, BC031700,
Species
mouse
UniGene ID
Mm.4502
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.