mouse LTK shRNA silencing Adenovirus

Name
Ad-m-LTK-shRNA

Cat No
shADV-263960

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ltk.

shADV-263960

Ad-m-LTK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ltk (leukocyte tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.

Gene ID

17005

Gene Name (Vector)

leukocyte tyrosine kinase

Gene Symbol

Ltk

ORF Size (aa)

2484

ORF Size (bp)

2484 bp

RefSeq ID

NM_206941

RefSeq Synonyms

NM_206942, NM_206941, NM_203345, NM_008523, BC141299, BC047138,

Species

mouse

UniGene ID

Mm.1740

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.