mouse LRAT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Lrat.
shADV-263790
Ad-m-LRAT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Lrat (lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1300010A18Rik; AI449251
Description (Vector)
Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.
Gene ID
79235
Gene Name (Vector)
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
Gene Symbol
Lrat
ORF Size (aa)
696
RefSeq ID
NM_023624
RefSeq Synonyms
NM_023624, BC141378, BC141375,
Species
mouse
UniGene ID
Mm.33921
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.