mouse LNX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Lnx1.
shADV-263547
Ad-m-LNX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Lnx1 (ligand of numb-protein X 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Lnx
Description (Vector)
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity)|Function: Isoform 2 provides an endocytic scaffold for IGSF5/JAM4 (By similarity).
Gene ID
16924
Gene Name (Vector)
ligand of numb-protein X 1
Gene Symbol
Lnx1
ORF Size (aa)
1887
ORF Size (bp)
1887 bp
RefSeq ID
NM_010727
RefSeq Synonyms
NM_010727, NM_001159580, NM_001159579, NM_001159578, NM_001159577, BC139771,
Species
mouse
UniGene ID
Mm.440403
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.