mouse KHDRBS3 shRNA silencing Adenovirus

Name 
Ad-m-KHDRBS3-shRNA
Cat No 
shADV-262786
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Khdrbs3.

shADV-262786
Ad-m-KHDRBS3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Khdrbs3 (KH domain containing, RNA binding, signal transduction associated 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Etle; Salp; SLM-2; Slm2; T-STAR
Description (Vector)
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.
Gene ID
13992
Gene Name (Vector)
KH domain containing, RNA binding, signal transduction associated 3
Gene Symbol
Khdrbs3
ORF Size (aa)
1041
RefSeq ID
NM_010158
RefSeq Synonyms
NM_010158, BC057577, BC031507,
Species
mouse
UniGene ID
Mm.17964

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.