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mouse KDM4C shRNA silencing Adenovirus

Name 
Ad-m-KDM4C-shRNA
Cat No 
shADV-262765
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Kdm4c.

shADV-262765
Ad-m-KDM4C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kdm4c (lysine (K)-specific demethylase 4C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2410141F18Rik; AA517467; Gasc1; Jmjd2c
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Gene ID
76804
Gene Name (Vector)
lysine (K)-specific demethylase 4C
Gene Symbol
Kdm4c
ORF Size (aa)
3165
ORF Size (bp)
3165 bp
RefSeq ID
NM_144787
RefSeq Synonyms
NM_144787, NM_001172095, BC042424, BC020180,
Species
mouse
UniGene ID
Mm.209059

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.