mouse KCNJ1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Kcnj1.
shADV-262649
Ad-m-KCNJ1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kcnj1 (potassium inwardly-rectifying channel, subfamily J, member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Kir1.1; ROMK; Romk2
Description (Vector)
In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium.
Gene ID
56379
Gene Name (Vector)
potassium inwardly-rectifying channel, subfamily J, member 1
Gene Symbol
Kcnj1
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_019659
RefSeq Synonyms
NM_019659, NM_001168354, BC020525,
Species
mouse
UniGene ID
Mm.390168
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.