mouse KCNE1 shRNA silencing Adenovirus

Name 
Ad-m-KCNE1-shRNA
Cat No 
shADV-262619
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Kcne1.

shADV-262619
Ad-m-KCNE1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kcne1 (potassium voltage-gated channel, Isk-related subfamily, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Isk; MinK; nmf190
Description (Vector)
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
Gene ID
16509
Gene Name (Vector)
potassium voltage-gated channel, Isk-related subfamily, member 1
Gene Symbol
Kcne1
ORF Size (aa)
390
ORF Size (bp)
390 bp
RefSeq ID
NM_008424
RefSeq Synonyms
NM_008424, BC094276,
Species
mouse
UniGene ID
Mm.299425

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.