mouse KATNB1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Katnb1.
shADV-262576
Ad-m-KATNB1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Katnb1 (katanin p80 (WD40-containing) subunit B 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2410003J24Rik; KAT
Description (Vector)
Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth (By similarity).
Gene ID
74187
Gene Name (Vector)
katanin p80 (WD40-containing) subunit B 1
Gene Symbol
Katnb1
ORF Size (aa)
1977
ORF Size (bp)
1977 bp
RefSeq ID
NM_028805
RefSeq Synonyms
NM_028805, BC045200,
Species
mouse
UniGene ID
Mm.28382
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.