mouse JTB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Jtb.
shADV-262541
Ad-m-JTB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Jtb (jumping translocation breakpoint). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Gm622
Description (Vector)
Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity).
Gene ID
23922
Gene Name (Vector)
jumping translocation breakpoint
Gene Symbol
Jtb
ORF Size (aa)
441
RefSeq ID
NM_206924
RefSeq Synonyms
NM_206924, BC008139,
Species
mouse
UniGene ID
Mm.13912
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.