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mouse INTU shRNA silencing Adenovirus

Name 
Ad-m-INTU-shRNA
Cat No 
shADV-262307
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Intu.

shADV-262307
Ad-m-INTU-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Intu (inturned planar cell polarity protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
9230116I04Rik; 9430087H23Rik; mKIAA1284; Pdzd6; Pdzk6
Description (Vector)
Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity).
Gene ID
380614
Gene Name (Vector)
inturned planar cell polarity protein
Gene Symbol
Intu
ORF Size (aa)
2829
ORF Size (bp)
2829 bp
RefSeq ID
NM_175515
RefSeq Synonyms
NM_175515, BC132387, BC125523,
Species
mouse
UniGene ID
Mm.432345

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.