mouse ING2 shRNA silencing Adenovirus

Name 
Ad-m-ING2-shRNA
Cat No 
shADV-262236
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ing2.

shADV-262236
Ad-m-ING2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ing2 (inhibitor of growth family, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2810011M06Rik; Ing1l; Ing2b; P33ING2
Description (Vector)
Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
Gene ID
69260
Gene Name (Vector)
inhibitor of growth family, member 2
Gene Symbol
Ing2
ORF Size (aa)
846
RefSeq ID
NM_023503
RefSeq Synonyms
NM_023503, BC138229, BC096433,
Species
mouse
UniGene ID
Mm.430733

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.