mouse IMPDH2 shRNA silencing Adenovirus

Name 
Ad-m-IMPDH2-shRNA
Cat No 
shADV-262226
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Impdh2.

shADV-262226
Ad-m-IMPDH2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Impdh2 (inosine 5′-phosphate dehydrogenase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IMPD
Description (Vector)
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Gene ID
23918
Gene Name (Vector)
inosine 5'-phosphate dehydrogenase 2
Gene Symbol
Impdh2
ORF Size (aa)
1545
ORF Size (bp)
1545 bp
RefSeq ID
NM_011830
RefSeq Synonyms
NM_011830, BC052671, BC010314,
Species
mouse
UniGene ID
Mm.6065

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.