mouse IL1R2 shRNA silencing Adenovirus

Name 
Ad-m-IL1R2-shRNA
Cat No 
shADV-262139
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Il1r2.

shADV-262139
Ad-m-IL1R2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Il1r2 (interleukin 1 receptor, type II). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD121b; Il1r-2
Description (Vector)
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Gene ID
16178
Gene Name (Vector)
interleukin 1 receptor, type II
Gene Symbol
Il1r2
ORF Size (aa)
843
RefSeq ID
NM_010555
RefSeq Synonyms
NM_010555, BC032962,
Species
mouse
UniGene ID
Mm.1349

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.