mouse IFT57 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ift57.
shADV-261950
Ad-m-IFT57-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ift57 (intraflagellar transport 57). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4833420A15Rik; Esrrbl1; Hippi; MHS4R2
Description (Vector)
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Gene ID
73916
Gene Name (Vector)
intraflagellar transport 57
Gene Symbol
Ift57
ORF Size (aa)
1290
ORF Size (bp)
1290 bp
RefSeq ID
NM_028680
RefSeq Synonyms
NM_028680, BC138144, BC138143,
Species
mouse
UniGene ID
Mm.404371
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.